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2-Bromopalmitoyl-CoA (Synonyms:S-(2-Bromopalmitoyl)coenzyme A;Coenzyme A, S-(2-bromohexadecanoate))
目录号 : FM256 纯度 : BR/95%以上 品牌 : CHEMSOON Cas No. : 37785-38-9
2-bromopalmitate (2BP) is an irreversible inhibitor of manymembrane-associated enzymes. 1 It was initially reported as aninhibitor of β-oxidation 2,3 but later shown to inhibit mono-, di-,and triacylglycerol transferases, fatty acyl CoA ligase, glycerol-3-phosphate acyltransferase, as well as nonlipid processingenzymes such as NADPH cytochrome-C reductase andglucose-6-phosphatase at submillimolar concentrations. 2BP inhibition is thought to block protein palmitoylation byinhibiting a family of conserved protein acyl transferases(PATs). 8 Mammals express 23 distinct PAT enzymes that arepresumed to regulate the profile of palmitoylated proteins,either by PAT localization, protein interactions, or active siteselectivity.
2-Bromopalmitoyl-CoA
Cas No. : 37785-38-9
规格编号 纯度 包装 库存 价格 拼团价
FM256-2mg BR/95%以上 2mg
面议
FM256-5mg BR/95%以上 5mg
面议
产品名称:2-Bromopalmitoyl-CoA
其他名称:S-(2-Bromopalmitoyl)coenzyme A;Coenzyme A, S-(2-bromohexadecanoate);DL-2-Bromopalmitoyl-Coenzym A
 CAS:37785-38-9
结构信息
分子式  C37H65BRN7O17P3S 分子量  1084.84
相关文献

1.Profiling Targets of the Irreversible Palmitoylation Inhibitor 2-Bromopalmitate.  DOI:10.1021/cb400380s  PMID:23844586